通过双重机制,Tribbles 伪激酶 3 促进了肠道病毒 A71 感染

Huiqiang Wang1,2,3, Ke Li3, Boming Cui1,3

  • 1CAMS Key Laboratory of Antiviral Drug Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

PubMed
概括

特里布尔斯3 (TRIB3) 通过稳定其受体和促进病毒RNA复制来帮助肠道病毒A71 (EV-A71) 感染. 在小鼠中降低TRIB3水平显著降低了EV-A71的严重性和致命性.