对抗微生物治疗方案的结果和微生物角质炎中的抗生素表的发展进行比较:埃及亚历山大的一项前性队列研究
Amira A Nayel1,2, Noha A Hamdy3, Tamer H Massoud4
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
概括
这项研究确定了亚历山大微生物角质炎的常见原因及其对抗菌素的敏感性. 推的治疗方法包括莫西弗洛克萨治疗格拉姆阳性细菌角膜炎和纳塔米加沃里可纳治疗真菌角膜炎.
科学领域:
- 眼科医生 眼科 眼科
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- 微生物角质炎中抗菌素耐药性是一个越来越令人担忧的问题.
- 这项研究是第一个在埃及亚历山大探索微生物角质炎的研究.
- 了解局部耐药性模式对于有效治疗至关重要.
研究的目的:
- 在亚历山大确定引起微生物角质炎的病因病因.
- 为了确定孤立微生物的抗微生物敏感性.
- 为了比较不同实证局部抗微生物疗法的结果.
主要方法:
- 在亚历山大主要大学医院进行了前性队列研究.
- 从角膜取物中分离了微生物,并测试了它们对抗菌素的敏感性.
- 根据治疗结果对细菌性角质炎 (BK),真菌性角质炎 (FK) 和混合真菌/细菌性角质炎 (MFBK) 的患者进行了比较.
主要成果:
- 凝聚酶阴性葡萄球菌 (CoNS),Pseudomonas aeruginosa和阿斯伯吉洛斯种类. 是最常见的微生物.
- 观察到CoNS对万科米辛 (VAN) 和莫西素 (MOX) 的高度敏感性.
- 与单一治疗相比,纳他素 (NT) 和伏利可纳 (VRC) 的联合治疗对真菌角膜炎的治疗结果更好.
结论:
- 经验性莫西弗洛克萨 (MOX) 推用于治疗格拉姆阳性细菌角膜炎.
- 建议加提夫洛克萨用于治疗格拉姆阴性细菌角膜炎.
- 建议在严重的真菌角膜炎中使用纳塔amycin (NT) + voriconazole (VRC) 组合治疗.
关键词:
抗生素抗生素表的方法抗微生物耐药性 抗微生物耐药性细菌性角质炎是一种细菌性角质炎.角膜的发病情况经验性治疗是经验性的治疗.强化的抗生素强化的抗生素.菌的角质炎是一种真菌性角质炎.微生物角质炎的发生在上皮质化之前的时间的愈合 的愈合更多相关视频
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