[女性肺癌患者的整体状况不明原因下降]
J Brägelmann1, S Becker2, D Stenzel2
1Klinik für Endokrinologie, Diabetologie und Stoffwechsel, Universitätsmedizin Essen, Hufelandstraße 55, 45147, Essen, Deutschland. Johannasibylle.braegelmann@uk-essen.de.
一名接受杜尔瓦卢马布治疗肺癌的患者出现了严重的虚弱和吐,最初怀疑是化疗副作用. 诊断显示出新发的糖尿病和甲状腺功能低下症,被确定为免疫治疗的免疫相关不良事件.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
背景情况:
- 肺癌患者通常接受化疗或免疫疗法.
- 像杜尔瓦卢马布这样的免疫检查点抑制剂 (ICI) 可以引起与免疫相关的不良事件 (irAEs).
- 区分IRE与其他疾病对于有效的患者管理至关重要.
研究的目的:
- 为了调查正在接受治疗的肺癌患者突然恶化的原因.
- 为了区分化疗副作用和与免疫相关的不良事件.
主要方法:
- 患者病史和身体检查.
- 诊断工作包括血糖和甲状腺功能测试.
- 审查目前的癌症治疗方案.
主要成果:
- 诊断显示了酸性糖尿病和严重的甲状腺功能低下症.
- 患者正在接受杜尔瓦卢马布 (免疫检查点疗法),而不是化疗.
- 这些症状归因于durvalumab的免疫相关不良事件.
结论:
- 使用杜尔瓦卢马布的免疫检查点治疗可以表现为新发糖尿病和甲状腺功能低下症.
- 这些内分泌系统疾病的及时诊断和管理对于患者的康复至关重要.
- 区分免疫相关的不良事件与传统化疗副作用至关重要.
更多相关视频
11:31Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
Published on: May 20, 2016
09:02Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
Published on: June 28, 2018
相关概念视频
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Other Pulmonary Disorders
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
