相关实验视频

Updated: Jul 5, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
10:29

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

1.1K

确定针对Exportin-1的新型抑制剂,用于潜在的COVID-19治疗

Tanuj Sharma1, Tanmoy Mondal2,3, Sajid Khan4

  • 1Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Gangnam-gu, Seoul, 06273, Republic of Korea.

Archives of microbiology
|January 19, 2024
PubMed
概括

研究人员使用计算方法确定了核出口蛋白1 (XPO1) 的新型抑制剂. 这些化合物在实验室测试中显示出降低SARS-CoV-2感染的潜力,这表明了潜在的新型抗病毒疗法.

关键词:
停靠对接 停靠对接机器学习 机器学习分子动力学分子动力学这就是SARS-CoV-2病毒.一个XPO1一个XPO1一个XPO1

更多相关视频

Author Spotlight: Development of a Large-Scale, Reproducible Production Method for Exosome Mimetics Using Magnetic Nanoparticles05:36

Author Spotlight: Development of a Large-Scale, Reproducible Production Method for Exosome Mimetics Using Magnetic Nanoparticles

Published on: January 26, 2024

1.4K
Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics06:00

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics

Published on: May 14, 2016

11.0K

相关概念视频

Nuclear Export01:42

Nuclear Export

The nucleus restricts several proteins within and allows others to pass. The restricted proteins possess a nuclear retention sequence or NRS, anchoring them to the nuclear lamins and preventing their transport to the cytosol. The non-restricted proteins, after their synthesis, are transported to their site of action, such as the cytosol or other organelles, with the help of nuclear export signals or NES.
NES are of three types- the canonical 10-residue long leucine-rich signal and other...
3.6K