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Updated: Jul 5, 2025

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
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Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

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造咖啡:一个序列特定的粗粒度能量函数,用于模拟DNA-蛋白质复合体

Debayan Chakraborty1, Balaka Mondal1, D Thirumalai1,2

  • 1Department of Chemistry, The University of Texas at Austin, 105 E 24th Street, Stop A5300, Austin 78712, Texas, United States.

Journal of chemical theory and computation
|January 19, 2024
PubMed
概括

我们开发了COFFEE,这是DNA-蛋白相互作用的计算模型. 咖啡精确模拟复杂的结构和动态,帮助基因表达和染色体折叠的研究.

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