药品和治疗委员会在支持乌干达医院最佳抗菌剂使用中的作用:混合方法研究
Isaac Magulu Kimbowa1, Moses Ocan1, Jackson Mukonzo1
1Department of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.
PloS one
|January 19, 2024
概括
药物和治疗委员会 (MTC) 的结构,包括会员和小组委员会,对于乌干达医院的最佳抗菌使用至关重要. 需要进行培训,以加强MTC的运营,以便更好地管理抗微生物药物.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 传染性疾病 传染性疾病
- 医院 医院 药房 医院药房
背景情况:
- 药物和治疗委员会 (MTC) 在医院药物管理中发挥着越来越重要的作用.
- 关于MTC结构对最佳抗菌剂使用的影响的数据有限,特别是在低收入和中等收入国家 (LMICs).
- 了解MTC结构对于改善资源有限的环境中的抗菌药物管理至关重要.
研究的目的:
- 探索MTC在支持乌干达医院最佳抗菌药物使用中的结构和作用.
- 确定促进抗微生物药物管理的MTC的关键结构组成部分.
- 提供证据来加强LMICs中的MTC.
主要方法:
- 在乌干达的区域转诊,普通和私人非营利性医院中采用了一种解释性顺序混合方法方法.
- 通过采访员管理的问卷从MTC主席/秘书收集的定量数据.
- 通过对长期MTC成员进行关键信息人采访收集的定性数据用于三角测量.
主要成果:
- 16家医院已经建立了MTC,平均存在5.6年,拥有7-14名成员 (中位数为10人),主要是药剂师和临床专家.
- 常见的小组委员会包括供应链 (14),抗菌药物管理 (13),和感染控制 (12).
- 医疗药物协会为配方制品的抗菌选择/评估提供了支持 (14/16),并开展了抗菌管理活动 (15/16).
结论:
- MTC成员和小组委员会是有效的抗菌选择和最佳使用的关键结构元素.
- 乌干达的MTC积极参与抗菌药物管理,支持适当的抗菌药物的使用.
- 建议卫生部加强培训,以优化所有医院的MTC运营结构.
相关概念视频
Combined Effects of Drugs: Synergism
3.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.9K
Drug Control Governance: Regulatory Bodies and Their Impact
160
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
160
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180
Antibiotic Selection
53.7K
Overview
53.7K
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
410
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
410


