口服抗癌药物的坚持与短期医疗保健资源利用之间的关联:2010-2018年基于索赔的分析
Ami Vyas1, Megha A Parikh2, Patrick J Campbell2
1Department of Pharmacy Practice and Clinical Research, College of Pharmacy, University of Rhode Island, Kingston.
Journal of managed care & specialty pharmacy
|January 19, 2024
概括
患者对口服抗癌药物的坚持显示出对医疗保健资源利用率 (HRU) 的不同影响. 坚持患者的办公室访问更多,但整体HRU类似,这表明需要进一步研究.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
- 药物经济学 药物经济学
背景情况:
- 有限的证据表明,口服抗癌药物的坚持如何影响癌症患者的医疗保健资源利用率 (HRU).
- 了解这种关系对于优化癌症护理和资源配置至关重要.
研究的目的:
- 在现实患者群体中调查口服抗癌药物的坚持与随后的医疗保健资源利用率 (HRU) 之间的关联.
- 确定与不同癌症类型的药物坚持相关的HRU的特定模式.
主要方法:
- 使用商业索赔数据 (Optum Clinformatics® Data Mart) 从2010年至2017年进行的回顾性队列研究.
- 药物坚持度通过在开始后的前6个月内覆盖日数 (PDC) 的比例来评估.
- 在随后的6个月内使用多变量负二项式回归来评估所有原因的HRU.
主要成果:
- 超过37,000名患者开始服用口服抗癌药物,51.9%的患者坚持服用.
- 坚持与更多的医生办公室和门诊访问有关,特别是在肝癌患者中.
- 肺癌患者的急诊室访问量增加,而肝癌患者的住院时间和停留时间更高. 结肠直肠癌患者在坚持治疗时,住院次减少,住院时间缩短.
结论:
- 在初始口服抗癌药物治疗后,坚持和不坚持的患者之间,医疗保健资源利用率 (HRU) 一般相似.
- 附加患者的办公室和门诊访问量略高,可能是由于持续的监测.
- 需要进一步的研究来探索口服抗癌药物对HRU的长期影响.
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