COVID-19对药物使用模式的影响:国家医院的一个案例研究
Minh-Anh Le-Dang1, Hai-Yen Nguyen-Thi1, Luyen Pham Dinh1
1University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam.
PloS one
|January 19, 2024
概括
越南的COVID-19大流行影响了越南的门诊药物使用,抗高血压剂和β-阻断剂等心血管药物的处方增加,而抗血压剂的准备增加,尽管整体药物消费保持稳定.
科学领域:
- 药理学和药理学流行病学
- 公共卫生和传染病.
- 老年医学 老年医学
背景情况:
- COVID-19大流行和相关的公共卫生措施在全球范围内显著影响了门诊药物使用.
- 关于大流行对越南老年人处方模式的具体影响的数据有限.
- 了解这些变化对于老年护理和流行病后恢复的公共卫生政策至关重要.
研究的目的:
- 分析越南老年人在COVID-19大流行期间门诊药物使用模式的变化.
- 为了比较国家老年医院COVID-19大流行早期爆发前后的药物处方趋势.
- 为了确定特定的药物类别,在利用方面经历了显著的变化.
主要方法:
- 从2016年1月到2022年12月的门诊处方和索赔数据的回顾性分析.
- 数据被分为两段时间:大流行前 (2020年1月至2020年12月) 和大流行初期 (2021年1月至2022年12月).
- 药物使用量以每月1000份处方 (DDD/1000P) 的定义每日剂量来衡量.
- 使用自回归集成移动平均线 (ARIMA) 评估药物使用变化的中断时间序列分析.
主要成果:
- 分析了超过170万份处方,期间间患者年龄的中位数从58岁增加到67岁.
- 心血管药物,特别是心脏疗法,β-阻断剂和抗高血压药物,显示消费量显著增加.
- 观察到使用抗炎药物制剂的显著增加,与抗炎和抗风湿药物消费的减少形成鲜明对比.
结论:
- COVID-19导致越南老年人门诊药物使用的情况发生了重大变化,心血管药物使用量明显增加.
- 抗胺制剂使用量的增加需要进一步调查,特别是与NSAID消费量的下降相结合.
- 持续监测至关重要,以充分了解大流行对老年人药物使用模式的长期影响.
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