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PINK1与核酸和素的相互作用

Zhong Yan Gan1,2, Sylvie Callegari1,2, Thanh N Nguyen1,2,3

  • 1Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Science advances
|January 19, 2024
PubMed
概括

基尼三酸盐 (KTP) 不能激活与帕金森病相关的PINK1激酶,这是由于固态碰撞. 能够使KTP结合的突变可能通过调节PINK1活性为帕金森病提供新的治疗策略.

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