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针对皮肤黑色素瘤的CD4+ T细胞免疫包括多方面的MHC II依赖反应

Emma G Bawden1,2, Teagan Wagner1, Jan Schröder3

  • 1Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.

Science immunology
|January 19, 2024
PubMed
概括

细胞毒性CD4+ T细胞对于抗瘤免疫至关重要,可以通过TNF-α和FasL消除黑色素瘤. 抗原呈现细胞和黑色素瘤细胞上的主要基因相容性复合体II类 (MHC II) 表达驱动了这种反应.

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