膜溢出预示着在持续的门诊腹膜透析患者的预后不佳
Fengping Zhang1,2, Ting Xiang2, Xiaoran Feng2
1Department of Nephrology, Jiujiang NO.1 People's Hospital, Jiujiang, China.
PloS one
|January 19, 2024
概括
在持续的门诊腹膜透析 (PD) 患者中,多发性溢出是常见的. 这种并发症显著增加了整体和心血管死亡的风险,独立于其他健康因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床医学 临床医学
- 流行病学 流行病学
背景情况:
- 胸腔溢液是连续的门诊腹膜透析 (PD) 的已知并发症.
- 有限的数据存在于多发性病患者的多发性溢血的预后影响.
- 这项研究解决了关于流和PD结果之间的关联的可靠数据的需求.
研究的目的:
- 为了验证在患有PD的患者中流和预后之间的关联.
- 在这个人群中量化与肺溢出相关的死亡风险.
- 调查与PD中多叶膜溢出相关的因特定死亡率.
主要方法:
- 一项多中心队列研究选了1162名PD患者.
- 患者被分为多发性溢出和非多发性溢出组.
- 用调整的分析和倾向性得分匹配 (PSM) 来估计死亡的危险比率.
主要成果:
- 在8.9%的PD患者中发生多流.
- 调整后的分析显示,在患有多发性溢液的患者中,所有原因死亡 (3.06) 和心血管死亡 (3.78) 的危险比率显著增加.
- PSM证实了所有原因死亡率 (3.56) 的高危险比率. 没有发现与传染病或其他死亡原因的关联.
结论:
- 流是PD患者经常出现的并发症.
- 胸腔溢液与整体和心血管死亡率的增加显著相关.
- 这种关联独立于PD患者的潜在疾病和临床指标.
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