喘作为COVID-19儿童和青少年住院的危险因素:一项回顾性队列研究
Shana T Lara1,2, Lisa E Rein1,2, Amanda M Simanek2,3,4
1From the Institute for Health & Equity, Medical College of Wisconsin, Milwaukee, WI.
The Pediatric infectious disease journal
|January 19, 2024
概括
患有喘的儿童面临着因2019年新冠病毒病 (COVID-19) 住院住院的更高风险. 这项研究证实了喘是危险因素,强调了儿童喘患者持续预防和监测COVID-19的必要性.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 在儿童中喘和COVID-19住院治疗之间的关联方面存在不同的结果.
- 喘和COVID-19住院患者表现出因种族,种族,社会经济地位和地理位置而受到影响的差异.
- 之前的研究没有考虑到这种关联中的邻里环境.
研究的目的:
- 调查儿童和青少年中喘和COVID-19住院治疗之间的关联.
- 通过童年机会指数来确定邻里环境是否会改变这种关联.
- 检查社会人口统计学因素和诊断季节作为调节者.
主要方法:
- 一个回顾性队列研究,对28997名儿童和青少年诊断出COVID-19在密尔沃基县,WI (2020年3月 - 2022年5月).
- 使用混合效应的物流回归,随机拦截人口普查区域以考虑地理变化.
- 模型根据个人社会人口统计学因素进行调整,并评估了社区层面的童年机会指数.
主要成果:
- 喘病史是儿童和青少年COVID-19住院治疗的重要风险因素.
- 住院率因人口普查区而异,独立于童年机会指数.
- 诊断的季节并没有缓解喘和住院之间的关联.
结论:
- 喘是儿童群体中COVID-19住院治疗的确诊危险因素之一.
- 患有喘的儿童需要对COVID-19感染进行仔细监测和随访.
- 持续采取公共卫生措施预防COVID-19对于这个弱势群体至关重要.
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