2019年儿童严重和危急冠状病毒疾病的危险因素
Kyung-Shin Lee1, Ye Kyung Kim2, Youn Young Choi1,3
1From the Public Health Research Institute, National Medical Center.
The Pediatric infectious disease journal
|January 19, 2024
概括
严重的COVID-19在儿童中在三角洲变种期间比Omicron更为常见. 接种疫苗可以预防严重疾病,特别是危急病例,有助于识别高风险儿科人群.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病2019 (COVID-19) 通常在儿童中呈现温和,但可能发生严重后果.
- 了解儿科COVID-19的临床变异和风险因素对于有效管理至关重要.
研究的目的:
- 在儿童中分析严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 的临床表现.
- 确定患有严重或危急COVID-19的高风险儿科组.
- 为了比较Delta和Omicron变种占主导地位的时期之间的临床特征.
主要方法:
- 全国范围的研究使用国家健康保险服务 (NHIS) 数据库和韩国疾病控制和预防机构-COVID-19-NHIS队列.
- 包括在三角洲 (2021年7月至2022年1月) 和欧米克朗 (2022年1月至3月) 期间的儿科COVID-19病例 (20岁以下).
- 分析临床表现,风险因素和疫苗接种情况.
主要成果:
- 与Omicron时期相比,在三角洲时期,严重或危急的COVID-19病例更频繁.
- 奥米克朗时期的肺炎和病住院人数增加,神经系统表现的可能性更高.
- 严重COVID-19的危险因素因年龄和变种而异;接种疫苗显著降低了严重疾病的风险.
结论:
- 发现有助于识别患有严重或危急COVID-19的高风险儿童,需要密集医疗支持.
- 结果可以为儿童群体制定有针对性的疫苗接种政策提供信息.
- 了解变种特定的临床表现是管理儿科COVID-19的关键.
更多相关视频
09:03Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
4.8K
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
2.8K
相关概念视频
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Pneumonia I: Introduction
239
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
239
Acute Respiratory Failure-III
187
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
187
Immunodeficiency Diseases
941
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
941
Pulmonary Tuberculosis I
243
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
243
Attention-Deficit/Hyperactivity Disorder
68
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
68
