在新生儿群体中使用博托克斯治疗腹和腹
Nathan Lu1, Nadine Haykal1, Jennifer L McCoy1
1University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Department of Otolaryngology, Pittsburgh, PA, United States of America.
American journal of otolaryngology
|January 19, 2024
概括
毒素 (BoNT) 注射可以安全地治疗新生儿的,改善呼吸道保护并减少分泌物. 需要进一步的研究来确定这个人群的最佳剂量.
科学领域:
- 新生儿护理 新生儿护理
- 儿科神经学 儿科神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 在有呼吸道受损或吞困难的新生儿中,尿病的管理至关重要.
- 毒素 (BoNT) 用于老年人群的阴毛病,但缺乏对新生儿的研究.
- 本研究探讨了BoNT在新生儿分泌物管理中的安全性和有效性.
研究的目的:
- 评估毒素 (BoNT) 注射用于治疗新生儿的安全性和有效性.
- 评估BoNT对这种脆弱人群的分泌管理和气道保护的影响.
主要方法:
- 对接受超声导向BoNT注射到唾液腺 (下下和腺) 的新生儿 (≤12个月) 的回顾性审查.
- 收集关于患者人口统计,临床结果,呼吸道干预和养状况的数据.
- 对注射频率,剂量和并发症的分析.
主要成果:
- 六名新生儿接受了BoNT注射,83%的新生儿经历了注射后脱和/呼吸暂停的减少.
- 50%的患者氧气需求降低,需要吸气,而33%的患者在注射后需要进行外科手术.
- 没有报告注射相关并发症;50%需要重复注射.
结论:
- 超声导向的BoNT注射是一种安全的,非侵入性的新生儿的选择.
- BoNT可以改善呼吸道的保护,并减少新生儿的分泌负担.
- 进一步的研究是必不可少的,以确定最佳的BoNT剂量每个腺体的新生儿.
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