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临床预测工具,用于识别患肺栓塞风险的儿童
Tanatuch Tiratrakoonseree1, Suwanat Charoenpichitnun2, Rungrote Natesirinilkul3
1Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Thrombosis research
|January 19, 2024
概括
这项研究开发了一种新的临床预测工具,用于诊断泰国儿童的儿科肺栓塞 (PE). 2或更高的分数表明PE,提高了这种情况的诊断准确性.
科学领域:
- 儿科医学 儿科医学
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 儿童肺栓塞 (PE) 诊断是具有挑战性的,因为非特异性症状.
- 成人预测工具不适合儿童群体.
- 需要准确的诊断工具,以便及时检测儿童的PE.
研究的目的:
- 开发泰国儿科PE的临床预测模型.
- 评估泰国儿科人口中现有的PE预测工具.
- 为了提高儿童PE的诊断准确度.
主要方法:
- 对接受CT肺血管造影的儿童 (≤18岁) 进行多中心回顾性研究.
- 在PE阳性和PE阴性组之间的临床表现和VTE风险因素的比较.
- 使用后勤回归和性能评估 (灵敏度,特异性,AUC) 开发一个预测模型.
主要成果:
- 包括104名儿童:43名 (41.3%) 患有PE阳性,61名 (58.7%) 患有PE阴性.
- 有意义的预测因素:先天性心脏病/肺部手术,血栓性,以前的静脉动脉,性综合征,胸痛.
- 评分≥2的模型实现了74.4%的灵敏度,75.4%的特异性和0.809的AUC.
结论:
- 成功开发了泰国儿童儿科PE的新型临床预测工具.
- 该工具表现出令人满意的性能和验证.
- 在被研究的儿科患者群体中,分数≥2表明PE.
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