一种"性气味":瘤相关发症中的嗅觉光环
Irene Florean1, Pietro Vergobbi1, Barbara Tomasino2
1Department of Medical Area, University of Udine, Udine, Italy.
Epilepsy & behavior : E&B
|January 19, 2024
概括
患有瘤相关的患者经历嗅觉光时,常常在部和前部区域出现病变. 这些光环,虽然可能表明特定的大脑区域,但不会影响发作结果或手术后瘤复发.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 与瘤相关的 (TRE) 是原发性脑瘤 (PBT) 患者发作的重要原因.
- 嗅觉光环是罕见的,但潜在的有价值的发作表现.
- 描述TRE中嗅觉光的神经解剖学基础对于理解发作的起源至关重要.
研究的目的:
- 确定患有PBT和与瘤相关的发症患者的临床解剖学概况,呈现嗅觉光环.
- 在这个患者队列中调查嗅觉光环与外科手术结果之间的相关性.
主要方法:
- 在2010年至2019年期间,对患者进行了一项追溯的单心研究,这些患者接受了涉及叶和胰岛的PBT手术.
- 收集的数据包括神经放射学,神经心理学和神经生理学发现.
- 用MRI减去分析来确定病变位置.
主要成果:
- 嗅觉光环患者的最大病变重叠在左侧嗅觉皮质,双边海马体,左侧杏仁体,右侧罗兰 operculum,右下额头环,右中间状环中观察到.
- 嗅觉光环的存在或类型没有显著影响术后发作结果或瘤复发.
- 发作控制不受嗅觉光环的存在或类型的影响.
结论:
- 在TRE中嗅觉光环与前/半端部区域 (嗅觉皮质,杏仁体,海马体) 和特定的额头/部区域的参与有关.
- 这些发现表明,这些地区在产生嗅觉光方面可能发挥作用.
- 嗅觉光环,虽然经常被低估,但可以作为管理中的重要局部标志.
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