患有Phakic眼内透镜的患者的内皮细胞损失
Tadas Naujokaitis1, Gerd U Auffarth1, Grzegorz Łabuz1
1International Vision Correction Research Centre (IVCRC) und David J Apple International Laboratory for Ocular Pathology, Universitäts-Augenklinik Heidelberg, Deutschland.
Klinische Monatsblatter fur Augenheilkunde
|January 19, 2024
概括
面膜眼内透镜 (pIOLs) 的安全性有所改善,但内皮细胞损失仍然是一个问题. 谨慎的患者选择,监测和及时的探索对于安全的PIOL使用至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 角质科学 角质科学
背景情况:
- 70多年来,Phakic眼内透镜 (pIOL) 已经发展,但内皮细胞损失 (ECL) 仍然存在.
- 角膜内皮和角膜内皮之间的距离是影响ECL的关键因素.
- 前腔PIOLs通常比后腔PIOLs更高的ECL,因为它们靠近.
研究的目的:
- 分析影响内皮细胞损失的因素,在患有 phakic 眼内透镜的患者.
- 强调前腔深度和患者年龄在PIOL安全评估中的重要性.
- 为监测和管理PIOL植入后潜在的内皮细胞损失提供指导方针.
主要方法:
- 审查现有关于 phakic眼内透镜安全性和内皮细胞损失的研究.
- 分析PIOL类型,位置,前腔深度和ECL之间的关系.
- 评估患者特异性因素,包括年龄和内皮质储备,在pIOL结果.
主要成果:
- 内皮质细胞损失受到皮质皮质与角膜内皮质的距离的显著影响.
- 前腔深度对于虹膜固定PIOL来说至关重要,以保持内皮质的安全性.
- 前腔室因年龄而变浅,因此需要考虑PIOL的安全标准.
结论:
- 定期监测内皮细胞密度对于所有pIOL患者来说是必不可少的,因为个人之间存在差异.
- 如果检测到显著的,渐进的内皮细胞损失,建议立即进行PIOL扩张.
- 个人对内皮储备的评估,考虑到年龄和生理损失,对于安全有效的PIOL植入至关重要.
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