双A产前暴露与后代肥胖之间的关联:系统性审查
Jinjin Guo1, Keqin Liu1, Jixin Yang2
1School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Environmental pollution (Barking, Essex : 1987)
|January 19, 2024
概括
产前暴露在塑料中发现的 Bisphenol A (BPA) 化学物质中,与增加儿童肥胖风险有关. 这一系统性审查强调了越来越多的证据表明,怀孕期间的BPA与后代体重问题有关.
科学领域:
- 环境健康 环境健康
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
背景情况:
- 全球儿童超重和肥胖率正在上升,可能与环境化学物质暴露有关.
- 双A (BPA) 是塑料和树脂中常见的化学物质,引起了人们对其在肥胖中的作用的担忧.
- 怀孕和生命早期是发育的关键时期,使它们易受内分泌破坏性化学物质 (如BPA) 的影响.
研究的目的:
- 系统地审查关于产前双A (BPA) 暴露与后代肥胖之间的关系的人类研究.
- 澄清怀孕期间母亲尿液BPA水平与儿童随后的肥胖之间的联系.
主要方法:
- 主要科学数据库 (PubMed,科学网等) 的系统文献搜索. 在2023年7月之前.
- 包括13项主要研究,检查产前BPA水平和后代肥胖指标 (BMIz分数,腰围等). ) 的情况.
- 使用NOS,OCEBM和GRADE指南评估的方法质量,证据水平和证据确定性.
主要成果:
- 在13项审查的研究中,有8项发现产前BPA暴露与后代肥胖增加之间存在显著联系.
- 产前BPA暴露似乎会增加儿童肥胖的风险.
- 根据后代的年龄和性别,发现了潜在的效果变化.
结论:
- 产前双甲 (BPA) 暴露与后代肥胖的风险增加有关.
- 需要进一步的研究来确定因果关系,并了解不同发育阶段和性别之间的机制.
- 公共卫生策略可能需要考虑在怀孕期间减轻BPA暴露.
关键词:
体重指数 (BMI) 的z-分数BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA BPA孕产妇暴露的母亲暴露.肥胖问题 肥胖问题系统性审查 系统性审查更多相关视频
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