压力疼痛敏感性和时间型:对中年芬兰人的基于人口的研究
Eveliina Heikkala1, Petteri Oura2, Juhani Määttä2
1Research Unit of Population Health, University of Oulu, Oulu, Finland; Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland; Wellbeing Services County of Lapland, Rovaniemi, Finland.
The journal of pain
|January 19, 2024
概括
晚间类型的男性表现出增加的疼痛敏感性,特别是当他们患有心理健康障碍时. 这突显了昼夜节律对疼痛感知和风险的影响.
科学领域:
- 时间生物学 时间生物学
- 疼痛医学 医学 疼痛医学
- 精神病学是一个精神病学.
背景情况:
- 晚间时间型与更高的疼痛患病率有关.
- 关于时间型与客观疼痛敏感度指标的关联存在有限的研究.
- 心理健康,失眠和慢性疼痛可能会调节这种关系.
研究的目的:
- 为了研究时间型和压力疼痛敏感性之间的关联.
- 探索心理健康障碍,失眠和慢性肌肉骨疼痛的缓解作用.
- 分析时间型与疼痛敏感性关系中的性别差异.
主要方法:
- 利用了1966年北芬兰出生队列 (n=4,962) 的数据.
- 通过使用早晨-晚上问卷来评估时间型.
- 使用标准化协议测量压力疼痛值和耐受性.
- 雇用性别分层后勤回归,调整共变量和测试相互作用.
主要成果:
- 与早晨类型相比,晚间类型的男性表现出明显更高的低疼痛门和耐受率.
- 心理健康障碍大大放大了晚间类型男性的低疼痛值相关性.
- 在女性中,相关性较少明显,并且在统计学上无意义.
结论:
- 时间型在调节疼痛敏感性方面发挥着重要作用,特别是在男性中.
- 精神健康障碍的存在加剧了晚间时间型男性的疼痛敏感性.
- 这些发现强调了在疼痛评估和管理中考虑昼夜类型学的重要性.
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