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Updated: Jul 5, 2025

Presynapse Formation Assay Using Presynapse Organizer Beads and “Neuron Ball” Culture
10:17

Presynapse Formation Assay Using Presynapse Organizer Beads and “Neuron Ball” Culture

Published on: August 2, 2019

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在Munc18-1中与疾病相关的突变使突触Doc2耗尽

Noah Guy Lewis Guiberson1, Luca S Black1, Jillian E Haller1

  • 1Helen and Robert Appel Alzheimer's Disease Research Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA.

Brain : a journal of neurology
|January 19, 2024
PubMed
概括

STXBP1脑病变源于Munc18-1的突变. 这项研究表明,Munc18-1结合伙伴Doc2A和Doc2B也变得功能障碍,这解释了疾病的复杂性和患者症状的变化.

关键词:
在Munc18-1-1中使用.在STXBP1中使用.在 doc2 doc2 中脑病变 - 脑病变是一种脑病变.突触突触是突触的组成部分.

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