缓解了喘患者的不良呼吸结果:匹配的回顾性队列研究
Hywel Jones1, Bethan Cumins2, Rebecca Cannings-John3
1Division of Population Medicine, Cardiff University, Cardiff.
概括
与普通人群相比,喘症患者面临更高的呼吸道感染 (RTIs) 和抗生素处方风险. 这凸显了持续监测和潜在的再治疗策略的需要.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 一般实践一般实践
- 流行病学 流行病学
背景情况:
- 喘症状缓解可以导致初级保健中的"解决喘"代码.
- 关于这些患者随后出现恶化和呼吸道感染 (RTIs) 的风险的数据有限.
研究的目的:
- 评估患有已缓解喘的个体出现不良呼吸系统结果的风险.
- 对照组包括活跃的喘患者和没有喘的人.
主要方法:
- 使用英格兰临床实践研究数据链接 (2010-2019) 的回顾性队列研究.
- 分析了已解决喘,活跃喘和非喘个体的匹配队列.
- 负双项回归评估了恶化,RTIs和抗生素使用的发病率比率 (IRR).
主要成果:
- 与活跃喘相比,解决了喘队列的住院和咨询症状明显减少了喘恶化.
- 对于RTIs或流感/肺炎的住院率在喘和非喘组之间是相似的.
- 解决了喘患者的一般诊所咨询率较高,用于较低的RTIs和抗生素处方.
结论:
- 与一般人群相比,被编码为已解决的喘患者的一般诊断RTIs和抗生素处方风险增加.
- 这些发现表明,系统地重新评估症状和及时重新启动喘治疗可能有好处.
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