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宽探测器4DCT图像的运动校正用于心脏再同步治疗计划

Ashish Manohar¹, James Yang², Jed D Pack³

¹Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA; Department of Radiology, Stanford University, Stanford, CA, USA; Cardiovascular Institute, Stanford University, Stanford, CA, USA.

Journal of cardiovascular computed tomography

|January 19, 2024

概括

在心脏4DCT成像中,ResyncCT运动校正显著减少了人造物质,提高了心脏再同步治疗 (CRT) 领先位置的左心室机械激活估计的准确性.

科学领域:

心脏病学心脏病学
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

在心脏再同步治疗 (CRT) 中,最佳的领先位置针对的是最新机械激活的左心室 (LV) 段.
精确估计LV机械激活对于CRT成功至关重要.

研究的目的:

评估ResyncCT心脏4DCT运动校正算法的可行性.
评估ResyncCT能够改善CRT位的LV机械激活估计的能力.

主要方法:

利用了CRT计划/升级患者的全心周期4DCT图像.
将ResyncCT算法应用于运动损坏的4DCT图像,以获得运动纠正的图像.
在72个内心段中估计开始缩短 (TOS) 的时间,并使用虚假异步指数 (FDI) 量化运动工件.

主要成果:

通过ResyncCT显著降低了运动工件 (外国直接投资:28.9%与47.0%相比,p < 0.001).
在运动校正后,在50%的受试者中观察到统计学上不同的TOS估计 (p < 0.05).
43%的LV自由墙段在校正后被重新归类为最佳的放置地点.

结论:

在宽探测器心脏4DCT中,ResyncCT有效地减少了运动工件.
该算法产生了显著不同的TOS估计,并改变了最佳的领先位置位置的识别.
通过使用宽探测器4DCT成像,ResyncCT显示出增强CRT规划的前景.

关键词:

心脏4DCT是指心脏的4DCT.心脏再同步治疗心脏再同步治疗机械激活的LV机械激活运动纠正运动纠正

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