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Updated: Jul 5, 2025

Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4
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对离子通道的配体的识别:TRPM2

Yushu Gu1, Miaomiao Liu1, Linlin Ma1,2

  • 1Griffith Institute for Drug Discovery, Griffith University, 46 Don Young Rd, Brisbane, Queensland, 4111, Australia.

Chembiochem : a European journal of chemical biology
|January 19, 2024
PubMed
概括

碰撞诱导的亲和力选择质谱 (CIAS-MS) 直接识别TRPM2通道的配体. 这种方法简化了与TRPM2相关的疾病,如阿尔茨海默氏症和帕金森症的药物发现.

关键词:
在CIAS-MS中,我们可以看到:TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2TRPM2碰撞诱导激活的发生.离子通道 离子通道蛋白质 - 配合物复合物复合物

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