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双特异的BCMA/CD24CAR-T细胞控制多发性骨髓瘤的生长

Fumou Sun1, Yan Cheng1, Visanu Wanchai1

  • 1Myeloma Center, Winthrop P. Rockefeller Institute, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.

Nature communications
|January 19, 2024
PubMed
概括

新的仿真抗原受体 (CAR) 针对CD24的T细胞疗法显示出治疗多发性骨髓瘤的前景. 这些CD24-CAR-T细胞增强了巨细胞对残留癌细胞的清除,改善了现有的BCMA-CAR-T治疗方法.

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