怀孕期间的寨卡病毒感染和垂直传播:病例报告和特异性细胞介导免疫反应
Stéphanie Hindle1,2, Agnès Depatureaux3,4, Samuel Fortin-Dion3,4
1Centre d'infectiologie mère-enfant (CIME), Centre de recherche du CHU Sainte-Justine, 3175 Côte Sainte-Catherine, Room 7. 9. 61, Montreal, Quebec, H3T 1C5, Canada.
Archives of virology
|January 19, 2024
概括
在怀孕期间感染寨卡病毒 (ZIKV) 可以导致出生缺陷. 这项研究发现ZIKV信封蛋白在孕妇中强烈刺激了干扰素- (IFN-γ),表明免疫反应.
科学领域:
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 孕妇感染寨卡病毒 (ZIKV) 与先天性异常有关,严重程度与感染时的妊娠年龄相关.
- 评估孕妇群体中ZIKV暴露和免疫反应对于了解传播和疾病结果至关重要.
相关概念视频
Development of Immunocompetence
309
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
309
Immune Response Against Viral Pathogens
789
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
789


