通过FFAR4激活,通过阻断呼吸链复杂组合和相关的线粒体代谢,抑制肺腺癌

Zhe Wang1, Jinyou Li2, LongFei Wang3

  • 1Wuxi School of Medicine, Jiangnan University, Wuxi, China.

概括

自由脂肪酸受体4 (FFAR4) 在肺腺癌 (LUAD) 中降低,与生存率较差相关. FFAR4的激活抑制了LUAD细胞的生长,并改变了新陈代谢,这表明它是诊断和治疗的目标.

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