疫情期间用聚烯膜提供ECMO支持的结果:一项回顾性队列研究
Natalia Valenzuela-Faccini1, Claudia Poveda-Henao2,3, Catalina Flórez-Navas1
1Critical care resident, Universidad de La Sabana, Chía, Colombia.
BMC pulmonary medicine
|January 19, 2024
概括
聚烯 (PP) 氧化膜在COVID-19大流行期间是一种可行的体外膜氧化 (ECMO) 策略. 尽管由于较低的氧气转移,PP膜需要更频繁的更换,但PP膜增加了重症患者的ECMO可用性.
科学领域:
- 关键护理医学 关键护理医学
- 生物材料科学 生物材料科学
- 传染性疾病 传染性疾病
背景情况:
- 由于COVID-19的流行,造成了严重的供应短缺,影响了体外膜氧化 (ECMO) 的可用性.
- 聚烯 (PP) 膜被用作ECMO期间氧化的应急措施.
- 这项研究比较了PP与聚甲基 (PMP) 氧化膜在ECMO患者中的临床结果.
研究的目的:
- 与聚甲基 (PMP) 膜相比,评估使用聚烯 (PP) 氧化膜进行ECMO的患者的临床结果.
- 评估PP膜在供应链中断期间作为替代品的可行性和有效性.
主要方法:
- 在2020年至2021年期间,对152名ECMO患者进行了回顾性队列研究.
- 膜类型 (PP与PMP) 的分析,膜变化的原因,并发症和死亡率.
- 在PP和PMP膜组之间的临床结果的比较.
主要成果:
- 聚烯 (PP) 膜需要更换的频率明显高 (63.1%) 与PMP膜相比 (32.8%31.9%,p=0.022).
- 低氧转移是PP膜更换的主要原因 (56.2%).
- 在PP组 (68.7%) 与PMP组 (34.2%31.9%,p=0.001) 相比,脏替代疗法是较为频繁的并发症,死亡率没有显著差异.
结论:
- 聚烯 (PP) 氧化膜在SARS-CoV-2大流行期间被证明是一种有用和可行的策略.
- 使用PP膜增强了ECMO支持的可用性,以帮助面临资源限制的重症患者.
- 在关键供应短缺的情况下,PP膜提供了一个可行的替代方案,尽管它们需要对氧气传输和潜在并发症进行更密切的监测.
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