在乌干达和赞比亚为艾滋病毒感染者提供基于电话的戒烟计划:随机对照试验的研究协议
Heather Wipfli1, Jim Arinaitwe2, Fastone Goma3
1Keck School of Medicine, Department of Preventative Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90033, USA. hwipfli@usc.edu.
Addiction science & clinical practice
|January 19, 2024
概括
这项研究测试了尼古丁替代疗法 (NRT) 和短信短信用于非洲艾滋病毒感染者戒烟. 调查结果将为成本有效的干预措施提供信息,以减少这一弱势群体的烟草使用.
科学领域:
- 公共卫生 公共卫生
- 全球健康 全球健康
- 艾滋病毒/艾滋病研究研究
背景情况:
- 烟草使用是艾滋病毒感染者 (PLWH) 的重要关注点.
- 尼古丁替代疗法 (NRT) 和基于短信的干预措施对戒烟有希望.
- 由于复杂的医学和心理社会因素,撒哈拉以南非洲 (SSA) 的PLWH需要量身定制的干预措施.
研究的目的:
- 测试NRT和在乌干达和赞比亚的PLWH中定制的基于SMS的戒烟干预措施的有效性.
- 与标准护理相比,评估NRT和SMS联合干预措施的有效性.
主要方法:
- 一项随机对照试验,涉及800名使用烟草的成年PLWH.
- 参与者被随机分配到四个组:标准护理 (SOC),SOC + NRT,SOC + SMS,或SOC + NRT + SMS.
- 主要结局:在6个月后通过尿路中可提宁检测出戒烟的证据. 二次结果包括在多个时间点自我报告和生物化学验证的禁欲.
主要成果:
- 研究正在进行中; 结果正在等待.
- 本议定书概述了评估新型戒烟策略的方法.
结论:
- 该研究将提供有关在SSA中为PLWH提供戒烟干预措施的有效性,可行性和适用性的见解.
- 调查结果可以为全球PLWH减少烟草消费的成本有效策略提供信息.
- 成功的干预可以为PLWH带来显著的健康和经济效益.
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