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阻断GPR15可以在体内对抗因特林依赖的T细胞肠道回归

Sebastian Schramm1, Li-Juan Liu1, Marek Saad1

  • 1Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Journal of Crohn's & colitis
|January 20, 2024
PubMed
概括

G蛋白结合受体15 (GPR15) 对于T细胞向肠道转移至关重要. 针对GPR15提供了一种有前途的治疗策略,通过阻断T细胞的招募来治疗炎症性肠病 (IBD).

关键词:
在 GPR15 中使用.炎症性肠病是一种炎症性肠病.发现T细胞定位粘附性 粘附性 粘附性 粘附性我已经看到了Vedolizumab.

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