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多种类基准分析用于LC-MS/MS验证和性能评估在自下而上的蛋白质组学

Tobias Jumel1, Andrej Shevchenko1

  • 1Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Pfotenhauerstraße 108, 01307 Dresden, Germany.

Journal of proteome research
|January 20, 2024
PubMed
概括

我们开发了LFQ_bout,这是一个新的基准工具,用于验证液体染色学-并联质谱 (LC-MS/MS) 蛋白质组学工作流. 该软件通过识别和报告数据处理中的常见错误来提高量化准确性.

关键词:
这就是DIA-NNN的意义.这是LC-MS/MS.准确度 准确度 准确度 准确度 准确度一个基准的基准指标.数据独立获取 (DIA) 是指数据独立获取.不同的蛋白质组学分析.没有标签的量化 (LFQ)

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
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