静止反射失联率不受年龄的影响
Michele Brignole1, Antonella Groppelli1, Vincenzo Russo2
1IRCCS Istituto Auxologico Italiano, Faint and Fall Research Centre, Ospedale San Luca, Milan, Italy.
JACC. Clinical electrophysiology
|January 20, 2024
概括
在40岁以上的患者中,自发性静止失眠的发生率保持不变. 然而,随着年龄的增长,倾斜诱导的辅助性昏迷会减少,这挑战了它是倾斜诱导的失眠的概念.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 神经学 神经学
背景情况:
- 有证据表明,随着年龄的增长,管对心脏的影响会减少.
- 这种与年龄相关的阴道声调下降是一个已知的现象.
- 这项研究调查了这是否也会影响反射失眠中的 asystole.
研究的目的:
- 要确定与年龄相关的阴道效应的减少是否会影响自发反射失眠 (RS) 中的 asystole 发生率.
- 为了在不同年龄组中比较自发性心性事件的发生率与由头向上倾斜测试 (HUT) 诱导的发生率.
主要方法:
- 从四项涉及40岁及以上患者的研究中进行了数据分析,其中包括疑似或确诊的RS.
- 植入式循环记录器 (ILR) 用于记录心性事件 (同>3秒或非同性心>6秒).
- 将ILR结果与头向上倾斜测试 (HUT) 的比较结果在同一患者队列中.
主要成果:
- 在1,046名不明原因昏迷的患者中,有201名 (19.2%) 经历了记录的心性事件.
- 通过ILR记录的自发性心性事件的发生率在三个年龄段 (≤60,61-72,≥73岁) 中是相似的,约为50%.
- 相反,由HUT诱导的心性昏迷在年轻患者中显著增加,并且随着年龄的增长而下降 (P=0.009).
结论:
- 根据ILR的记录,自发性静心反射失眠的发生率在40岁以上的患者中没有显著变化.
- 由头向上倾斜测试诱导的静止失眠在年轻人中更为普遍,并且随着年龄的增长而下降.
- 这些对比的发现质疑了人们普遍认为,反射失眠中的 asystole 在老年人中较少发生.
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