克罗地亚初生母亲的母乳中的多化二乙烯:2010年与2020年对比
Marija Dvoršćak1, Karla Jagić1, Ivana Jakovljević1
1Division of Environmental Hygiene, Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10001, Zagreb, Croatia.
Archives of environmental contamination and toxicology
|January 20, 2024
概括
在萨格勒布母亲的母乳中分析了多化二乙烯 (PBDE). 虽然BDE-99水平上升,但BDE-153水平保持不变,婴儿暴露低于健康风险值.
科学领域:
- 环境化学环境化学
- 毒理学 毒理学 毒理学
- 人类健康 人类健康 人类健康
背景情况:
- 聚二乙烯 (PBDE) 是持久性有机污染物,具有潜在的健康影响.
- 母乳是婴儿接触环境污染物的主要途径.
- 对母乳中PBDE的时间监测对于评估暴露趋势至关重要.
研究的目的:
- 来自克罗地亚萨格勒布的人类牛奶中选择的PBDE原体的时间趋势.
- 为了比较2010年和2020年的母乳样本中的PBDE含量.
- 根据估计的每日摄入量 (EDI) 来评估婴儿的潜在健康风险.
主要方法:
- 2010年和2020年,从扎格勒布的第一次母亲那里收集了人乳样本.
- 气色谱质谱法 (GC-MS) 用于量化七种PBDE同源物 (BDE-28, -47, -99, -100, -153, -154, -183).
- 进行了统计分析,以比较年间的水平,并与母亲因素和婴儿摄入量相关联.
主要成果:
- 与2010年相比,在2020年观察到BDE-99水平的统计学上显著增加.
- BDE-153是最频繁检测到的同源,并且在十年内没有显著下降.
- 2020年,总PBDE (ΣPBDEs) 的婴儿EDI较高,但仍低于已确定的健康风险值.
结论:
- 人母乳中的PBDE含量显示出特定于同源的时间趋势.
- 孕产妇的BMI与BDE-153水平呈正相关性.
- 在这个群体中,母乳消费对婴儿的健康风险很低,因为婴儿暴露于PBDE.
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