人工智能 (AI) - - 这是我们所知的毒素的终结 (我感觉很好)
Nicole Kleinstreuer1, Thomas Hartung2,3
1NIH/NIEHS/DTT/NICEATM, Durham, NC, USA.
Archives of toxicology
|January 20, 2024
概括
人工智能 (AI) 正在通过分析大量数据集来预测化学毒性和改善安全评估来彻底改变毒理学. 需要进一步开发以解决AI可解释性和数据偏差的监管接受.
科学领域:
- 毒理学 毒理学 毒理学
- 计算毒理学计算毒理学
- 化学安全 化学安全
背景情况:
- 毒理学正在从观察转向数据丰富,需要先进的计算方法.
- 毒理学数据的数量和复杂性日益增加,对传统分析提出了挑战.
- 人工智能 (AI) 为整合和解释各种毒理学数据集提供了强大的工具.
研究的目的:
- 探索人工智能在化学安全评估和毒理学方面的变革潜力.
- 突出AI在解决数据复杂性和增强毒理学评估方面的作用.
- 讨论人工智能集成在现代毒理学中的机遇和挑战.
主要方法:
- 机器学习 (ML),深度神经网络,大语言模型 (LLM) 和自然语言处理 (NLP) 的应用.
- 利用人工智能预测毒性终点,分析高通量数据,并从科学文献中提取信息.
- 利用人工智能生成合成数据,并通过概率输出加速定量风险评估.
主要成果:
- 人工智能方法已经在预测毒性,分析复杂数据和从文本中提取知识方面取得了成功.
- 人工智能技术通过量化不确定性和改进模型解释性来提高风险评估的承诺.
- 人工智能可以自动化数据捕获和分析,从而使毒理学研究更有效和更具预测性.
结论:
- 人工智能有潜力显著推进毒理学,使其更具预测性,基于机制和综合证据.
- 解决诸如模型解释性,数据偏差和透明度等挑战对于AI的监管采用至关重要.
- 多学科合作对于开发强大的,可解释的,以人为中心的毒理学AI系统至关重要.
相关概念视频
Issues And Trends In Healthcare Delivery System
5.6K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.6K
Current Trends in Nursing II
1.2K
Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
1.2K
Introduction to Cognitive Psychology
488
Cognitive psychology is the field of psychology dedicated to examining how people think. It attempts to explain how and why we think the way we do by studying the interactions among human thinking, emotion, creativity, language, and problem-solving, as well as other cognitive processes. Cognitive psychology studies how information is processed and manipulated in remembering, thinking, and knowing.
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
488
Control Systems: Applications
615
Electrical engineering plays a pivotal role in our daily lives, with control systems at the heart of many applications, from home appliances to sophisticated space shuttles. Control systems manage and regulate the behavior of devices and processes, ensuring they function safely, correctly, and efficiently.
In modern vehicles, control systems manage various functions to enhance performance and safety. The steering wheel and accelerator are primary inputs in a car's control system. The...
In modern vehicles, control systems manage various functions to enhance performance and safety. The steering wheel and accelerator are primary inputs in a car's control system. The...
615
Control Systems
1.1K
Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...
At the heart...
1.1K
Natural and Artificial Concepts
163
In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint...
163


