状微极体综合征:一个儿科病例系列
Jasmine Zacharias1, Uday Mandalia1, Jason Palman1
1West Hertfordshire Teaching Hospitals NHS Trust, Hertfordshire, England.
Skeletal radiology
|January 20, 2024
概括
儿童的状微极症综合征 (PMS) 呈现出数字胀. 磁力共振成像比X射线更具诊断性,揭示了可能与COVID-19血管病变相关的骨和软组织变化.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 放射学 放射学是一门学科.
- 传染病流行病学 传染病流行病学
背景情况:
- 管微极症综合征 (PMS) 是一种罕见的儿科疾病,影响数字,病因不明.
- 这项研究发生在英国COVID-19流行病的第二个峰值期间,观察了一群受影响的儿童.
研究的目的:
- 在儿科队列中描述PMS的临床和放射性特征.
- 为了调查PMS和COVID-19大流行之间的潜在关联.
主要方法:
- 对5名儿童的病例序列分析,这些儿童呈现了状腺胀和红斑.
- 进行了临床评估,实验室调查,X射线和磁共振成像 (MRI).
- 对所有参与者进行了风湿学工作.
主要成果:
- 4名儿童手部受伤,1名儿童脚部受伤;年龄从10.4岁到16.6岁不等.
- X射线显示,在某些情况下,微极管和骨再吸收,但MRI显示更广泛的骨髓,软组织胀和皮质侵蚀.
- 在急性临床背景下,MRI发现更具有病理性.
结论:
- 管微极形综合征的诊断从MRI中获益,因为它对骨髓胀和软组织异常的敏感性,超过了普通的X射线.
- 与COVID-19大流行病的时间关联表明,COVID相关的血栓友或免疫介导血管病症可能起到PMS的触发作用.
- COVID-19血管病变可能是前期综合征的以前未被识别的原因.
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