血中的度和所有原因的死亡风险在一般人群中
Paula Stürmer1, Katharina Susanne Weber2, Eike Andreas Strathmann2
1Institute of Epidemiology, Kiel University, Niemannsweg 11, 24105, Kiel, Germany. paula.stuermer@epi.uni-kiel.de.
European journal of nutrition
|January 20, 2024
概括
在德国的一项人口研究中,较高的血水平与女性的全因死亡风险增加有关,但男性没有. 由于女性发生的事件数量较少,需要进一步研究.
科学领域:
- 微量元素研究的研究.
- 人类健康与营养
- 流行病学 流行病学
背景情况:
- 是一种微量元素,与健康益处有关.
- 血和一般人群生存率之间的关联是未知的.
研究的目的:
- 为了研究血度与全因死亡率之间的关系.
- 在德国北部以人口为基础的队列进行的研究.
主要方法:
- 使用感应合的等离子体质量谱法测量血水平.
- 用于分析的Cox比例危险回归模型.
- 根据相关的混因素进行了调整.
主要成果:
- 平均随访时间为11年,99人死亡.
- 原始分析显示了血和死亡率之间的关联 (HR:1.07).
- 多变量调整使得该关联无意义 (HR:1.03).
- 性别分层分析显示,女性的死亡风险较高 (HR:1.11) 但男性的死亡风险较高 (HR:1.00).
结论:
- 血中较高的度与女性全因死亡风险增加有关.
- 在男性中没有发现任何显著的关联.
- 由于事件数量少,女性的发现需要谨慎解释.
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