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在莫亚莫亚病中,与直接和间接绕道结合相关的并发症:元分析

Sávio Batista¹, Stefan Koester², Anthony E Bishay²

¹School of Medicine, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373, Cidade Universitária, Ilha Do Fundão, Rio de Janeiro, RJ, 21941-590, Brazil.

Neurosurgical review

|January 20, 2024

概括

针对莫亚莫亚病 (MMD) 的联合绕道手术在儿科和成人患者中具有相似的并发症率. 缺血是这种MMD治疗后最常见的并发症.

科学领域:

神经外科神经外科
血管外科血管外科
神经学神经学

背景情况:

莫亚莫亚病 (MMD) 的管理往往涉及绕道复血管化以预防中风.
联合直接和间接 (CB) 绕道是MMD中使用的一种手术技术.
了解与CB旁路相关的并发症对于患者的治疗结果至关重要.

研究的目的:

系统地审查莫亚莫亚病 (MMD) 中联合直接和间接 (CB) 绕道的并发症.
分析和比较成人和儿科患者之间发生的并发症率,这些患者接受了为MMD而进行的CB绕行术.

主要方法:

按照PRISMA指南进行了一次系统的文献审查.
搜索的数据库包括PUBMED,科克兰图书馆,科学网络和CINAHL (1980-2022).
包括的研究报告了在MMD患者的CB绕道手术后3个月内出现的外科并发症.

主要成果:

分析了18项涉及1151名患者的研究.
整体并发症发生率为:出血0.04,缺血0.07,发作0.03.
缺血是最常见的并发症 (0.07率).
与成人相比,儿科患者在出血 (0.03 vs 0.06) 或缺血性 (0.12 vs 0.09) 并发症率上没有显著差异.

结论:

莫亚莫亚病 (MMD) 的联合绕道 (CB) 手术与显著的并发症率有关,主要是缺血.
儿童和成年人群体在CB绕道后表现出类似的出血和缺血并发症率.
这些发现有助于对MMD手术进行风险评估和患者咨询.

关键词:

绕道绕道是一个绕道.组合组合的组合组合复杂性复杂性复杂性进行元分析分析.莫亚莫亚莫亚莫亚莫亚系统性审查系统性审查

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