与健康对照组相比,患有炎症性肠病的人的食乳化剂暴露:有什么可担心的吗?
Natasha Katsoudas1, Paris Tavakoli2,3, Nan Wu2
1School of Medical, Indigenous and Health Science, University of Wollongong, New South Wales, Australia.
Inflammatory bowel diseases
|January 20, 2024
概括
患有炎症性肠病 (IBD) 的人消耗的乳化剂比健康人多. 然而,特定的炎症乳化剂的摄入量很低,这挑战了关于它们在食物中普遍存在的常见假设.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 微生物组和饮食研究研究
背景情况:
- 乳化剂被怀疑是炎症性肠病 (IBD) 病原体的贡献者.
- 对于已确定的IBD患者的乳化剂消费模式的研究有限.
研究的目的:
- 量化和比较IBD患者和健康对照 (HCs) 之间六种特定乳化剂的摄入频率.
- 调查IBD队列内的乳化剂暴露变化 (克罗恩病与性结肠炎,儿童与成人,活跃与缓解).
主要方法:
- 在一项澳大利亚前性队列研究中,对367名参与者 (176名IBD,191名HC) 的基线食物记录进行了分析.
- 通过审查食品成分清单,确定乳化剂暴露 (多聚酸盐-80,碳酸甲基纤维素,卡拉基南,桑坦,莱西丁,单和二甲) 的方法.
- 在不同参与者群体中对乳化剂摄入频率的统计比较,控制潜在的混因素.
主要成果:
- 在5022种分析的食品中,18%含有至少一种化剂.
- 与HC (2.3份) 相比,IBD参与者每日总乳化剂暴露量 (2.7份) 显著更高 (P=.02).
- 单和二甲酸糖,莱西丁和香是IBD患者中最常食用的乳化剂;没有记录过聚酸盐-80的暴露.
结论:
- 与健康对照组相比,患有IBD的个体对乳化剂的暴露增加.
- 观察到某些炎症乳化剂的摄入量较低或不存在,表明它们在食品供应中的实际流行率可能低于通常所认为的.
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