一种基于单体物理粒子的新方法,用于模拟心血管流体结构相互作用问题的模拟
Alessandra Monteleone1, Sofia Di Leonardo1, Enrico Napoli2
1Ri.MED Foundation, Palermo, Italy.
Computer methods and programs in biomedicine
|January 20, 2024
概括
使用不可压缩光滑粒子水力学 (ISPH) 的新型流体结构相互作用 (FSI) 方法为心血管生物力学提供了一种统一,高效的方法. 这种新的FSI方案准确地模拟软组织,克服了传统分区方法的局限性.
科学领域:
- 计算流体动力学 计算流体动力学
- 生物医学工程 生物医学工程
- 流体结构相互作用 (FSI)
背景情况:
- 传统的流体结构交互 (FSI) 方法使用独立解决器的分区方法,导致高计算成本.
- 这些方法对于研究心血管工程问题至关重要,因为血液流动和组织相互作用对生物力学至关重要.
研究的目的:
- 在不可压缩的光滑粒子水力学 (ISPH) 框架内提出一个新的FSI方案,避免合单独的溶剂.
- 开发一种计算效率高的FSI方法,适用于模拟心血管系统和生物软组织.
主要方法:
- 提出了一个统一的系统,ISPH粒子定义了流体和结构领域.
- 固体粒子由弹元件连接在一起,以计算恢复静止长度的力,集成到ISPH分数步骤程序中.
- 这种方法在单个框架内同时解决流体动力学和结构动力学.
主要成果:
- 在通道中使用柔性束的验证显示,在流体动力学和束变形方面与ANSYS®有很好的一致性.
- 与文学相比,对大动脉功能的应用在开放和关闭阶段显示出一致的动态.
- 该方法在模拟复杂的心血管生物力学方面被证明是有效的.
结论:
- 拟议的基于ISPH的FSI方法在计算上比传统方法更有效.
- 它克服了分区方法的缺点,能够准确模拟诸如大动脉合并等现象.
- 强调了该方法适用于软组织的适用性和模拟血栓栓塞事件的潜力.
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