在全球化的世界里,对生育问题风险因素的批判性系统审查和元分析
Rasha R Bayoumi1, Lisa Hurt2, Ning Zhang3
1University of Birmingham, Dubai Academic City, Dubai, UAE.
Reproductive biomedicine online
|January 20, 2024
概括
这项研究强调了全球南方地区被忽视的生育风险,确定了生殖器结核病,艾滋病毒,细菌性阴道炎和女性生殖器切割是对生殖健康的重大威胁,并增加了不孕症风险.
科学领域:
- 生殖健康 生殖健康
- 全球健康 全球健康
- 流行病学 流行病学
背景情况:
- 全球范围内提高生育意识的努力忽视了不成比例地影响全球南方妇女的风险.
- 关于这些人群中生育问题的特定风险因素存在重大知识差距.
研究的目的:
- 系统地审查和元分析与生育问题相关的风险因素.
- 解决全球南方地区对生育风险的忽视和受影响人口不成比例的问题.
主要方法:
- 通过MEDLINE,Embase,Cochrane图书馆和其他数据库识别的研究的系统审查和元分析.
- 包括与对照组评估风险因素暴露的研究;排除没有对照组的研究.
- 三位独立作者对数据进行选和提取;使用纽卡斯尔-太华尺度进行质量评估.
主要成果:
- 生殖器结核病显示,无法怀孕的风险增加了九倍 (OR 8.91).
- 人类免疫缺陷病毒 (OR 2.93) 和细菌性阴道炎 (OR 2.81) 几乎使风险增加了三倍.
- 女性生殖器切割/切割II/III类型 (OR 2.06) 将输卵管因子不孕症的风险增加了一倍.
- 血缘关系增加了产后死亡风险 (死产或1.28,新生儿死亡或1.57).
结论:
- 确定的风险因素通过多种途径影响生殖过程.
- 专注于相关指标的健康促进可以改善预防和早期发现全球南方的生育问题.
- 多因素风险概况需要将生育纳入全球卫生计划中.
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