与初级保健中抑郁老年人通常治疗相比,行为激活的成本效益:一个集群随机对照试验
Noortje P Janssen1, Gert-Jan Hendriks2, Renate Sens3
1Behavioural Science Institute, Radboud University, 6525 XZ Nijmegen, the Netherlands; Department of Primary and Community Care, Research Institute of Health Sciences, Radboud University Medical Centre Nijmegen, 6525 EZ Nijmegen, the Netherlands; Institute for Integrated Mental Health Care Pro Persona, 6525 DX Nijmegen, the Netherlands.
Journal of affective disorders
|January 20, 2024
概括
行为激活 (BA) 可能是晚年抑郁症的主要治疗方法,与通常治疗 (TAU) 相比,它具有潜在的成本效益. 然而,成本效益估计仍然存在显著的不确定性,排除了坚定的结论.
科学领域:
- 老年精神病学是一门精神病学专业.
- 卫生经济学 卫生经济学
- 临床心理学 临床心理学
背景情况:
- 晚年抑郁症显著影响生活质量和医疗保健成本.
- 行为激活 (BA) 是对老年人抑郁症的有效治疗方法.
- 对于晚年抑郁症,BA与通常治疗 (TAU) 的成本效益尚未得到充分确立.
研究的目的:
- 评估与TAU相比,BA在中度至重度抑郁症的老年人中的成本效益.
- 评估BA对抑郁反应,质量调整寿命 (QALYs) 和社会成本的影响.
主要方法:
- 一个集群随机控制的多中心试验与161名老年人 (≥65岁) 进行.
- 经济评估包括QALY和社会成本,并将缺失的数据归咎于此.
- 两变线性回归和引导被用于估计成本和效果差异.
主要成果:
- 与BA (€-485) 相比,社会成本没有显著下降.
- 在BA和TAU之间没有观察到抑郁反应 (QIDS-SR) 或QALY的显著差异.
- 发现BA平均占主导地位,但估计的不确定性很大.
结论:
- 虽然BA在治疗晚年抑郁症方面显示出具有成本效益的潜力,但目前的估计带有显著的不确定性.
- 可能需要进一步的研究来确认BA对老年人的成本效益.
- 调查结果表明,BA可能是一个可行的,可能节省成本的干预措施,但最终结论受到统计不确定性的限制.
更多相关视频
相关概念视频
01:30Electroconvulsive Therapy
41
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
41
01:24Operant Conditioning Intervention
58
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
In operant conditioning, behaviors that are...
58