疼痛与间接感受之间的关系:系统性审查和元分析
Annabel Horsburgh1, Simon J Summers2, Aidan Lewis1
1University of Canberra Research Institute for Sport and Exercise, Faculty of Health, University of Canberra, Bruce, Australian Capital Territory, Australia; Discipline of Psychology, Faculty of Health, University of Canberra, Bruce, Australian Capital Territory, Australia.
The journal of pain
|January 20, 2024
概括
患有慢性疼痛的个体表现出体感准确度下降和体感敏感度增加,尽管他们报告了对身体感觉的更高意识. 对急性和复发性疼痛状态需要进一步的研究.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 疼痛研究 疼痛研究
背景情况:
- 内感觉,感知身体内部的状态,对于平衡至关重要.
- 功能障碍的整体感受被假设在慢性疼痛的发展中发挥作用.
- 有限的研究已经探讨了具体在各种疼痛条件下的整感觉能力.
研究的目的:
- 系统地审查和分析现有的关于疼痛患者内感变化的文献.
- 与无痛对照人群相比,评估疼痛群体的整体感知准确性,敏感性和意识.
- 确定有关急性和复发性疼痛状态的整体感受研究中的差距.
主要方法:
- 在4个电子数据库中进行系统的文献搜索 (开始至2023年2月).
- 包括28项研究用于对整感准确性,敏感性和意识的元分析.
- 对所有包含的分析进行偏差风险和证据确定性的评估.
主要成果:
- 分析显示,慢性疼痛患者的整体感知精度显著降低,整体感知灵敏度增加.
- 亚组分析显示,基于测量工具的基础上,整感觉敏感性有所变化,对身体感觉的注意力更高,但报告的情绪反应性较低.
- 在慢性疼痛患者和健康对照人群之间,没有发现整体感知意识的显著差异.
结论:
- 患有慢性疼痛的人在感知身体内部信号时表现出较低的准确性,与他们自我报告的高度感知意识形成鲜明对比.
- 目前对急性和复发性疼痛的证据很少,需要对这些领域进行进一步的研究.
- 分析中证据的确定性非常低,因此需要谨慎地解释结果.
相关概念视频
Pain
481
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
481
Nociception
27.9K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
27.9K
Blood and Nerve Supply to the Bones
11.0K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
11.0K
Analgesia and Pain Management
625
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
625
Thermosensation
30.4K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
30.4K
Sensory Perception: Organization of the Somatosensory System
3.0K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
3.0K


