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Updated: Jul 5, 2025

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在晚期玻璃眼瘤中失败的轨道膜切除术中使用5-flourouracil进行内部轨道膜切除术的修订:三年后的结果
Sunil Ruparelia1, Paul E Rafuse2, Brennan D Eadie2
1Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, NS..
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
|January 20, 2024
概括
使用5-甲进行腹腔内切除术修复对于晚期青光瘤是有效的,在大多数患者中,在3年内达到目标眼内压力 (IOP). 这种玻璃眼瘤手术显示出有希望的结果,持续并发症最小.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
背景情况:
- 晚期玻璃眼常常需要手术干预来控制眼内压力 (IOP).
- 副结膜纤维化可能会损害初始玻璃眼手术的成功,需要修复手术.
研究的目的:
- 为了评估3年内腹腔内切除术修订的3年结果,增加了5-甲.
- 评估该修订技术在患有晚期青光瘤和子结膜纤维化患者的疗效和安全性.
主要方法:
- 对41名患者进行了回顾性队列研究,这些患者接受了腹腔内切除术修订.
- 主要结局:眼内压力 (IOP). 二次结果:药物使用,视力敏,视野和并发症.
- 最低3年的随访时间.
主要成果:
- 成功率 (IOP <15 mm Hg,>20%的减少) 是44% (完整) 和71% (合格) 在3年.
- 成功率 (IOP <12 mm Hg,>20%的减少) 为31% (完整) 和44% (合格).
- 过渡性低血压 (63%) 和低血压 (7.3%) 是主要的早期并发症;没有报告持续性并发症.
结论:
- 使用5-甲进行内侧带切除术修复是晚期玻璃眼瘤的有效手术选择.
- 该程序可以达到并保持低目标IOP长达3年.
- 这种技术为因子结膜纤维化而导致耐火性玻璃眼患者提供了可行的解决方案.
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