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患有非静脉性肝结节切除术的患者的复发性胆道炎:发病率和危险因素
Anouk G Overdevest1, Jeska A Fritzsche1, Mark A D Smit2
1Amsterdam UMC, Location University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, the Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands; Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, the Netherlands.
概括
复发性胆炎甚至可以发生在具有专利肝结节管 (HJ) 解剖的患者中. 这项研究发现,4.4%的患者经历了没有HJ狭窄的复发性胆管炎,男性性别和良性疾病是危险因素.
科学领域:
- 肝胆道和胰腺外科手术.
- 手术并发症 手术并发症
- 胃肠病学 胃肠病学
背景情况:
- 胆管炎是经过肝膜结节术 (HJ) 后的已知并发症,通常与静脉管狭窄症有关.
- 患有专利 (非静脉) HJ 的患者中胆道炎的发病率在很大程度上是未知的.
- 了解非静脉动脉炎的非静脉动脉炎对于改善手术后患者的治疗结果至关重要.
研究的目的:
- 为了确定患有非静脉性肝脏结节切除术 (HJ) 的患者中复发性胆道炎的发病率.
- 在没有HJ狭窄的情况下识别与复发性胆管炎相关的风险因素.
主要方法:
- 一个单一中心的回顾性队列研究包括了2015年至2022年间接受关节手术的患者.
- 主要结局是复发的非静脉性胆道炎.
- 使用后勤回归分析来确定复发性非静脉炎的危险因素.
主要成果:
- 在835名患有HJ的患者中,4.4% (31/698) 患有复发性胆结炎与非静脉动脉.
- 这些患者的中位数为7.0次胆管炎发作,其中34.6%需要住院治疗.
- 男性性别 (aOR 3.17) 和良性疾病 (aOR 2.97) 是非静脉炎的复发性胆管炎的重要危险因素.
结论:
- 大约4%的患者发展出复发性胆管炎,尽管他们已经获得了专利性肝脏结节术 (HJ).
- 男性性别和潜在的良性疾病被确定为关键风险因素.
- 这些发现凸显了需要警和潜在的针对性管理策略的需要,用于非硬膜性HJ的胆管炎.
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