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Updated: Jul 5, 2025

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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Published on: September 13, 2018

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LKB1-TSSK1B轴控制YAP酸化以调节Hippo-YAP通路的作用

Cho-Long Kim1, Su-Bin Lim1, Sue-Hee Choi1

  • 1Department of Biomedical Sciences, Graduate School, Ajou University School of Medicine, Suwon, 16499, South Korea.

Cell death & disease
|January 20, 2024
PubMed
概括

通过新的途径,TSSK1B酸化YES相关蛋白 (YAP),通过抑制细胞增殖和瘤转化,作为瘤抑制剂. 这一发现突显了Hippo-YAP通路中的新调节机制.

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