日本精神分裂症患者的死亡率
Nobuyuki Nomura1,2,3, Fuminari Misawa4, Yasuo Fujii4
1Department of Psychiatry and Psychotherapy, Section Evidence-Based Medicine, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Ismaningerstr. 69, 81675, Munich, Germany. nobuyuki.nomura@tum.de.
与一般人群相比,日本的精神分裂症患者面临的死亡率明显更高. 死亡的关键风险因素包括男性,年龄较大和巴比图拉剂使用.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在全球范围内,精神分裂症与死亡风险增加有关.
- 缺乏关于日本精神分裂症患者死亡率趋势的最新数据.
研究的目的:
- 为了评估日本精神分裂症患者的过度死亡率.
- 为了确定与这一群体的死亡率相关的风险因素.
主要方法:
- 对1699名被诊断为精神分裂症或精神分裂情绪障碍患者 (2013-2017) 的回顾性研究.
- 标准化死亡率 (SMRs) 将患者死亡率与一般人口进行比较.
- 后勤回归确定了死亡风险因素.
主要成果:
- 所有原因的SMR为2.18,表明死亡率是一般人口的两倍多.
- 非自然原因的SMR特别高,为5.07.
- 死亡风险增加与男性性别 (OR=2.24),晚年 (OR=1.12),和巴比图拉剂使用 (OR=8.17) 有关.
结论:
- 在日本,精神分裂症患者的死亡率仍然很高.
- 需要进一步的研究来监测这一人口群中的死亡率趋势.
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