后代的性别改变了怀孕早期脂肪和2岁的身体活动之间的关联 - - 光研究
Eva C Diaz1,2,3, David K Williams4, Erin K Howie5
1Arkansas Children's Nutrition Center, Little Rock, AR, USA. ECdiazfuentes@uams.edu.
International journal of obesity (2005)
|January 20, 2024
概括
怀孕早期的孕产妇肥胖与2岁女孩的体力活动降低有关,但男孩没有. 这项研究强调了产前营养对儿童活动水平的性别特异性影响.
科学领域:
- 人类发育生物学人类发育生物学
- 孕产妇和胎儿的健康状况
- 儿科的体育活动.
背景情况:
- 产前营养显著影响后代的行为,包括体力活动 (PA).
- 虽然动物模型显示母亲营养不足/营养过剩对后代PA的编程影响,但人类数据仍然有限.
- 这项研究调查了怀孕早期母亲脂肪和2岁后代PA之间的联系.
研究的目的:
- 评估怀孕早期母亲脂肪和2岁后代身体活动之间的关联.
- 探索产前和产后因素在这种关系中的作用.
- 为了确定后代的性别是否会改变母体脂肪和身体活动之间的关联.
主要方法:
- 153名妇女在怀孕早期 (<10周) 被录取.
- 在入学时测量了母亲的脂肪 (脂肪质量指数,FMI) 和PA.
- 后代的PA在2岁时客观地使用加速度计测量.
- 通用线性回归模拟了母亲FMI和后代PA的关联,将性别视为调节者.
主要成果:
- 在母体FMI和后代PA之间没有发现显著的双变异关联 (p=0.398).
- 母亲FMI与后代的性别相互作用:较高的母体FMI与女孩 (p=0.009) 的低PA相关,但与男孩 (p=0.376) 不相关.
- 具体来说,与男孩相比,具有较高母性FMI (≥7 kg/m2) 的2岁女孩表现出降低的PA.
结论:
- 怀孕早期母亲脂肪和后代身体活动之间的关联取决于性别.
- 在怀孕早期增加的母体脂肪与女孩在2岁时体力活动的减少有关.
- 这些发现表明,产前母亲脂肪可能会在后代中编程性别特定的身体活动行为.
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