饮食中的lyszyme和avilamycin调节了 brojlers的肠道健康,免疫力和生长速度
Mervat A Abdel-Latif1, Hatem S Abd El-Hamid2, Mohamed Emam3
1Department of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt. mervat.abdellatif@vetmed.dmu.edu.eg.
BMC veterinary research
|January 20, 2024
概括
在 brojlers中食lyszyme (LYZ) 补充剂改善了生长,肠道健康和免疫力,为avilamycin (AVI) 提供了一个安全的替代品. LYZ增强了与AVI相比的肠道完整性和免疫反应,表明其作为可持续料添加剂的潜力.
科学领域:
- 动物科学动物科学
- 禽类的营养 养
- 免疫学 免疫学 免疫学
背景情况:
- 在家禽中使用抗生素正在受到严格审查,这推动了对饮食里索酶 (LYZ) 等替代品的研究.
- 以前的研究表明,肉中的LYZ具有前途,但需要与已知添加剂,如阿维胺 (AVI) 进行直接比较.
- 这项研究调查了LYZ和AVI作为料添加剂的比较有效性.
研究的目的:
- 为了比较饮食中的lyszyme (LYZ) 和avilamycin (AVI) 对 brojler生长性能的影响.
- 评估LYZ和AVI对肉肠道健康和免疫反应的影响.
- 为了确定LYZ是否可以在肉的食中作为AVI的安全有效替代品.
主要方法:
- 120只肉被分为三个组:对照组 (标准饮食),AVI补充剂 (100毫克/公斤) 和LYZ补充剂 (90毫克/公斤).
- 在五周的时间里,监测了增长表现,料转换率和欧洲生产效率因子.
- 分析了阴茎中关键免疫基因 (IL-18,IFN-γ,IL-10,IL-2,GSH-PX) 的mRNA表达.
- 评估了血清免疫反应 (H5N1疫苗接种标位) 和肠道微生物群 (结肠杆菌计数).
主要成果:
- 与对照组相比,AVI和LYZ都显著改善了体重,料转换率和欧洲生产效率因子.
- 与对照组和AVI组相比,LYZ补充剂导致IL-2,IL-10,IL-18和GSH-PX的叶表达显著增加.
- 与AVI相比,LYZ更有效地提高了H5N1抗体标位和降低了大肠杆菌计数,同时改善了肠道完整性标记物 (VH和VH/CD).
结论:
- 食里索酶 (90毫克/公斤) 补充剂在改善肉生长,肠道健康和免疫反应方面表现出优于或与阿维拉米辛相当的疗效.
- 在肉的食中,LYZ可以被认为是阿维胺的安全有效替代品.
- 建议进行进一步的体外和体内研究,以探索LYZ对肠道微生物群的影响,并阐明其在商业肉中的作用机制.
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