维生素摄入量和牙周病:观察性研究的元分析
Nannan Mi1, Miaomiao Zhang1, Zheng Ying1
1Department of Stomatology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
BMC oral health
|January 20, 2024
概括
摄入较高的维生素A,维生素B复合物,维生素C,维生素D和维生素E与牙周病的风险降低有关. 这一元分析强调了这些必不可少的营养素在口腔健康中的保护作用.
科学领域:
- 营养科学 营养科学
- 口腔卫生流行病学 口腔卫生流行病学
- 预防性牙科 预防性牙科
背景情况:
- 牙周病是一种普遍存在的口腔炎症状况,具有重大公共卫生影响.
- 饮食因素,特别是维生素摄入量,越来越多地被认为是它们在调节疾病风险方面的潜在作用.
- 了解特定维生素消费与牙周病之间的流行病学相关性对于公共卫生建议至关重要.
研究的目的:
- 进行元分析,评估各种维生素的饮食摄入量与患牙周病的风险之间的流行病学关联.
- 综合观察性研究的证据,量化维生素消费与牙周病之间的关系.
- 确定可能对牙周病起保护作用的特定维生素.
主要方法:
- 在八个主要科学数据库中进行了全面的文献搜索.
- 来自23项观察性研究的数据,包括74,488名参与者,被纳入了元分析.
- 使用随机效应模型将几率比率 (OR) 和95%置信区间 (CI) 结合起来,并进行灵敏度分析.
主要成果:
- 摄入更多的维生素A (OR:0.788),维生素B复合物 (OR:0.884),维生素C (OR:0.875),维生素D (OR:0.964) 和维生素E (OR:0.868) 都与牙周病有显著的负相关性.
- 观察到的关联在留下一个漏洞的灵敏度分析中保持强,这表明研究结果的可靠性.
- 从包括的研究中,共有45个效果组为分析做出了贡献.
结论:
- 这一元分析表明,维生素A,维生素B复合物,维生素C,维生素D和维生素E的摄入与牙周病的风险之间存在显著的反向关系.
- 这些维生素的高摄入量似乎会对牙周病的发展产生保护作用.
- 这些发现强调了足够的维生素摄入对于预防牙周病的策略的重要性.
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