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Updated: Jul 5, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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FTO蛋白调节TGF-β信号通路,通过RNAN6-甲基氨酸修饰来诱导不明原因的复发性自发性流产

Jun Zhang1, Xinqiong Liu1, Yali Gao2

  • 1Department of Reproductive Medicine, Obstetrics and Gynecology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University), China.

The FEBS journal
|January 21, 2024
PubMed
概括

异常的RNA m6A修饰,特别是增加的FTO蛋白质,抑制MEG3稳定性和TGF-β1表达,影响未解释的复发性自发性流产 (URSA) 中的热囊细胞功能. 这揭示了URSA的新型治疗点.

关键词:
这是一种FTO蛋白质.在MEG3中,MEG3是MEG3,MEG3是MEG3.在RNA m6AA.在TGF-β1信号通路中.在YTHDC1蛋白质中,YTHDC1是

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