[儿童患有甲素耐药黄金葡萄球菌感染的患病率和危险因素]
P Marín Oliván1, S Ferrando Monleón, J R Bretón-Martínez
1Paula Marín Oliván, Servicio de Pediatría, Hospital Clínico Universitario, Valencia, Avenida de Blasco Ibáñez, 17, 46010 Valencia, Spain. paumaol@hotmail.com.
概括
甲素耐药黄金葡萄球菌 (MRSA) 感染影响15.4%的儿科患者,特别是住院患者. 住院和最近使用抗生素是MRSA的关键风险因素.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 儿童传染病 儿童传染病
背景情况:
- 黄金葡萄球菌是一种常见的病原体,其甲素耐药菌株 (MRSA) 构成了严重的公共卫生威胁.
- 了解儿童群体MRSA的流行病学和风险因素对于有效管理至关重要.
研究的目的:
- 确定特定卫生部门内儿科患者MRSA感染的流行率.
- 识别和比较与MRSA相关的风险因素与对甲素敏感的金黄色葡萄球菌 (MSSA) 感染.
- 分析MRSA和MSSA分离物的抗生素敏感性概况.
主要方法:
- 从2014年到2018年进行了一项回顾性,描述性和分析性研究.
- 由MRSA引起的感染与由MSSA引起的感染进行了比较.
- 采用二进制逻辑回归来分析MRSA感染的风险因素.
主要成果:
- 在162例金黄色葡萄球菌感染中,有25例 (15.4%) 是MRSA.
- 在住院儿童 (23.4%) 中,MRSA感染最为普遍.
- 在过去3个月内入院和接受抗生素治疗是MRSA感染的重要风险因素.
结论:
- 该研究强调需要重新考虑在住院儿童中怀疑葡萄球菌感染的经验治疗指南.
- 经验治疗方案应包括MRSA活性剂,特别是在最近接触过抗生素的患者中.
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